Animal Phenotyping Core
The Animal Phenotyping Core (APC) enables investigators to efficiently and cost effectively define the phenotypes of small rodents in ways that are relevant to the study of obesity, nutrition, and metabolism. The phenotyping capabilities of the APC range from whole animal measurements of body composition and energy utilization, to ex vivo measurements of substrate fluxes, to histological analyses of adipose tissue. In addition to the service provided, the APC provides expertise to guide both new and experienced investigators in the selection and use of techniques to define metabolic and related phenotypes.
Services
Adipose Tissue Morphology & Function
- Histologic and Morphometric Analysis
- Primary Cell Isolation and Analysis
- Differentiation of Adipocytes and Adipose Tissue Macrophages
- Metabolic Function of Adipose Tissue
- Adipose Tissue Transplantation
Energy Intake & Expenditure
- Indirect calorimetry plus food intake
- Feeding behavior
- Exercise calorimetry
- Temperature challenge and core body temperature measurements
Body Composition Analysis
- Body Composition in Conscious Animals – MRI Analysis
- Body Composition and Bone Density – DEXA Analysis
- Body Composition and Distribution - MicroCT Analysis
Metabolic Surgery
- Bariatric Surgery
- Autonomic denervations
- Gastrointestinal tube feeding
- Stereotactic brain cannulations & injections
- Bone marrow transplantation
Forms
Personnel
Yiying Zhang, PhD
- Associate Director
Anthony Ferrante Jr. MD, PhD
- Associate Director
Kaiying Guo, BS
- Technician
Licheng Wu, MA
- Technician
